A recent study published in Plos One compared the analytical performance of 17 C-reactive protein (CRP) point of care (POC) tests, with 8 being quantitative and 9 being semi-quantitative tests. For quantitative CRP tests, method comparison to the reference method and precision analysis (repeatability) according to CLSI EP09-A3 protocol were performed. Samples were collected from patients aged 2-65 years presenting with fever. The measurement range covered the CRP range relevant to guide antibiotic prescribing and triage patients.
QuikRead go® CRP POC test had the best agreement and lowest bias of all evaluated quantitative CRP tests. The repeatability of QuikRead go in the precision analysis was also good (CV 5.3%). Semi-quantitative tests showed considerable variation in analytical performance. The authors concluded that all quantitative tests performed well in the broad clinically relevant CRP range, whereas none of the semi-quantitative tests were acceptable for all cut-offs.
The full article is freely available here:
Analytical performance of 17 commercially available point-of-care tests for CRP to support patient management at lower levels of the health system
View more information about QuikRead go CRP from its product site.
Calarco et al. Analytical performance of 17 commercially available point-of-care tests for CRP to support patient management at lower levels of the health system. Plos One 2023; 18(1): e0267516. https://doi.org/10.1371/journal.pone.0267516