Norway
Global Fin Swe Nor Den Ger Cze Svk Pol Hun Nld Bel (nl) Bel (fr) USA
  • Logo
  • Produkter
  • Om oss
  • Nyheter
  • Kontakt oss
  • Bærekraft
  • Aidian Academy
  • Antibiotikaresistens
Søke
Logo
  • Pasientnær diagnostikk
  • Mikrobiologi
  • Hematologi
  • Molekylær mikrobiologi
  • Molekylær onkologi
  • Hygiene overvåking
  • RIA / kollagen
  • COVID-19
  • Andre
Pasientnær diagnostikk
  • QuikRead go
  • QuikRead 101
  • Aidian LF
  • Certest
  • Biosynex
  • Nova Biomedical
  • microINR
  • Acro™ Biotech
  • SD BIOSENSOR STANDARD™ F
  • bioLytical Laboratories INSTI®
  • Pulsar
  • GenSure
Les mer
QuikRead go
  • QuikRead go Instrument
  • QuikRead go easy CRP
  • QuikRead go CRP
  • QuikRead go CRP+Hb
  • QuikRead go wrCRP
  • QuikRead go wrCRP+Hb
  • QuikRead go HbA1c
  • QuikRead go Strep A
  • QuikRead go iFOBT
  • QuikRead go tilbehør
QuikRead go
Mikrobiologi
  • Uricult
  • Cultura M
  • MIKROGEN serologi
  • Meridian Immunoassays
  • Meridian Curian®
  • Reagena
  • Medac EIA
Les mer
Hematologi
  • Pixcell Medical – HemoScreen™
  • Norma Icon
Les mer
Molekylær mikrobiologi
  • ELITech Molecular Diagnostics
  • Meridian Alethia®
  • Meridian Revogene®
  • MIKROGEN molecular diagnostics
  • SD BIOSENSOR STANDARD™ M10
Les mer
Molekylær onkologi
  • Nucleix – Bladder EpiCheck®
Les mer
Hygiene overvåking
  • Easicult
  • Hygicult
  • Clean Card PRO
Les mer
RIA / kollagen
  • UniQ
Les mer
COVID-19
  • COVID-19-tester
Les mer
Andre
  • Grifols Promonitor®
  • Narkotika tester
Les mer
Logo
Lukk
  • Produkter
    • Pasientnær diagnostikk
      • QuikRead go
      • QuikRead 101
      • Aidian LF
      • Certest
      • Biosynex
      • Nova Biomedical
      • microINR
      • Acro™ Biotech
      • SD BIOSENSOR STANDARD™ F
      • bioLytical Laboratories INSTI®
      • Pulsar
      • GenSure
    • Mikrobiologi
      • Uricult
      • Cultura M
      • MIKROGEN serologi
      • Meridian Immunoassays
      • Meridian Curian®
      • Reagena
      • Medac EIA
    • Hematologi
      • Pixcell Medical – HemoScreen™
      • Norma Icon
    • Molekylær mikrobiologi
      • ELITech Molecular Diagnostics
      • Meridian Alethia®
      • Meridian Revogene®
      • MIKROGEN molecular diagnostics
      • SD BIOSENSOR STANDARD™ M10
    • Molekylær onkologi
      • Nucleix – Bladder EpiCheck®
    • Hygiene overvåking
      • Easicult
      • Hygicult
      • Clean Card PRO
    • RIA / kollagen
      • UniQ
    • COVID-19
      • COVID-19-tester
    • Andre
      • Grifols Promonitor®
      • Narkotika tester
  • Om oss
  • Nyheter
  • Kontakt oss
  • Bærekraft
  • Aidian Academy
  • Antibiotikaresistens

Populære produkter

Meridian Curian® Campy

Meridian Curian® Campy

Real-Time PCR Test Menu

Real-Time PCR Test Menu

ELITe BeGenius®

ELITe BeGenius®

Siste nytt

Se alt

Prepare for the Strep A season in the coming fall/winter

26. september 2023 | Nyheter, Produktnyheter

Get ready for flu season!

12. september 2023 | Nyheter, Produktnyheter

Free access clinical webinars on iMg, estimated plasma volume, fetal lactate, and many other topics

26. juni 2023 | Nyheter, Produktnyheter

  • Se alt
  • Ingen resultater
  • Loading...

Nyheter

Prepare for the Strep A season in the coming fall/winter

26. september 2023 | Nyheter, Produktnyheter

Get ready for flu season!

12. september 2023 | Nyheter, Produktnyheter

Tilbake til alle nyheter
8. september 2021
Nyheter,
AMR,
COVID-19

Antimicrobial resistance has accelerated during COVID-19

In the past decade, antimicrobial resistance (AMR) has been pointed out as an emerging global health threat. Now there are concerns that COVID-19 may have accelerated AMR due to increased use of antibiotics, although there is no scientific evidence that antibiotics would benefit in the treatment of COVID-19. Also, the increased number of hospital stays and invasive procedures in intensive care units (ICU) increased the risk for secondary bacterial infections that may require antibiotic therapy1. In ICU, ventilator associated pneumonia is a relatively common secondary infection, but patients also have urinary tract and bloodstream infections.

Antibiotics are commonly used in COVID-19 without confirmed secondary bacterial infection

At the beginning of the pandemic, antibiotics were widely used and prescribed especially for hospitalized COVID-19 patients often without an appropriate diagnosis of bacterial co-infection. As an example, in a multi-hospital cohort study in the USA, 57% of the 1705 patients received early empiric antibiotic treatment, of which only 3.5% had bacterial infection2. Another example from the USA is a study with almost 5000 participants demonstrating that during the first six months of the pandemic, 52% of the hospitalized COVID-19 patients had at least one antibiotic prescription and 36% multiple antibiotics. Up to 96% of these prescriptions were given empirically, without confirmation about the bacterial infection3. A review study evaluating the number of secondary infections in COVID-19 reported that secondary bacterial or fungal infections were in approximately 8% of the patients, but the antibiotics were prescribed for 72% of the patients4. In China, even up to 99% of the patients have received antibiotics without a diagnosed bacterial co-infection5.

CRP could aid in decreasing unnecessary antibiotic prescribing in COVID-19

Antimicrobial stewardship activities have slowly integrated into clinical guidelines that have started to recommend avoidance of antibiotics for mild and moderate COVID-19 unless there is clinical suspicion of secondary bacterial infection6,7. C-reactive protein (CRP) has been reported as a potential tool to guide antibiotic prescribing in secondary bacterial infections11. In COVID-19 patients, C-reactive protein levels are commonly slightly elevated between 20-50 mg/l8-10, whereas in hospitalized patients with secondary bacterial infection, CRP is significantly higher. A German study with 99 participants reported that patients admitted to the hospital, who develop a bacterial infection, had significantly higher CRP mean on admission (130 mg/l) and during hospital stay (mean highest CRP value 293 mg/l) compared to patients who did not have secondary infection 73 and 94 mg/l, respectively11. CRP had a sensitivity of 81% and a specificity of 76% for the detection of secondary bacterial infection, and the negative predictive value was 90% in patients with CRP < 172 mg/l. Therefore, CRP could be useful especially in ruling out bacterial coinfection and in decreasing unnecessary antibiotic prescribing.

References

  1. Cong W, Poudel AN, Alhusein N et al. Antimicrobial Use in COVID-19 Patients in the First Phase of the SARS-CoV-2 Pandemic: A Scoping Review. Antibiotics 2021; 10(6): 745.
  2. Vaughn VM, Gandhi TN, Petty LA et al. Empiric Antibacterial Therapy and Community-onset Bacterial Coinfection in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19): A Multi-hospital Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021; 72(10): e533-e541.
  3. The PEW Charitable Trust. Could Efforts to Fight the Coronavirus Lead to Overuse of Antibiotics?, 2021.
  4. Rawson TM, Moore LSP, Zhu N et al. Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020; 71(9): 2459-2468.
  5. Cao J, Tu W-J, Cheng W et al. Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020; 71(15): 748-755.
  6. National Institute for Health and Care Excellence (NICE). COVID-19 Rapid Guideline: Managing COVID-19: March 2021.
  7. World Health Organization. COVID-19 Clinical management - Living guidance, 2021.
  8. Chen N, Zhou M, Dong X et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet 2020; 395(10223): 507-513.
  9. Gao Y, Li T, Han M et al. Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19. J Med Virol 2020; 92(7): 791-796.
  10. Mo P, Xing Y, Xiao Y et al. Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China. Clin Infect Dis 2020.
  11. Pink I, Raupach D, Fuge J et al. C-reactive protein and procalcitonin for antimicrobial stewardship in COVID-19. Infection 2021.
Share
Facebook
Twitter
E-post

Aidian Norway AS

Fredrik Selmers vei 6,
0663 Oslo

Forespørsler
info@aidian.no

Salg
ordre@aidian.no

(+47) 66 78 56 30

Fakturaadresser

Fakturaadresse
(kun pdf-format) 922183848@xbs-salo.com

MVA-ID 922 183 848

  • Kontakt oss
  • Personvern
    • Personvernregler
    • Personvernerklæring
    • Varsel om informasjonskapsler
    • Social Media Policy (in English)
    • Slette samtykke til direkte markedsføring
  • Aidian Academy
  • Karriere
  • Bærekraft
  • Produkter
    • QuikRead go
    • QuikRead 101
    • Aidian LF
    • Easicult
    • Hygicult
    • Clean Card PRO
    • Uricult
    • Cultura M
    • UniQ
    • Certest
    • Biosynex
    • Nova Biomedical
    • microINR
    • Acro™ Biotech
    • SD BIOSENSOR STANDARD™ F
    • bioLytical Laboratories INSTI®
    • Pulsar
    • GenSure
    • MIKROGEN serologi
    • Meridian Immunoassays
    • Meridian Curian®
    • Reagena
    • Medac EIA
    • Pixcell Medical
    • Norma Icon
    • ELITech Molecular Diagnostics
    • Meridian Alethia®
    • Meridian Revogene®
    • MIKROGEN molecular diagnostics
    • SD BIOSENSOR STANDARD™ M10
    • Nucleix
    • Grifols Promonitor®
    • COVID-19-tester
    • Narkotika tester
Copyright © 2023 Aidian

Dette nettstedet bruker informasjonskapsler

Vi bruker informasjonskapsler til å tilpasse innhold og annonser, til å analysere bruken av nettstedet og til å gjøre tjenestene våre bedre.

Administrer innstillinger

Nødvendige (Obligatorisk)

Informasjonskapsler som nettstedet trenger for å kunne fungere slik det skal. Dette omfatter informasjonskapsler som benyttes til å gi tilgang til sikre områder, og informasjonskapsler som benyttes til å beskytte mot ondsinnet datakode (CSRF). Vær oppmerksom på at Crafts standardinformasjonskapsler ikke samler inn personopplysninger eller sensitive opplysninger. Crafts standardinformasjonskapsler samler ikke inn IP-adresser. Informasjonen de lagrer, sendes ikke til Pixel & Tonic eller andre tredjeparter.
— CraftSessionId
Provider: this site
Expiration: Session
Description: Craft benytter PHP-økter til å opprettholde økter over flere nettforespørsler. Dette gjøres gjennom PHP-øktinformasjonskapselen. Craft har gitt informasjonskapselen standardnavnet «CraftSessionId», men den kan gis nytt navn via konfigurasjonsinnstillingen for phpSessionId. Denne informasjonskapselen utløper når økten utløper.
— *_identity
Provider: this site
Expiration: Persistent
Description: Når du logger på kontrollpanelet, mottar du en godkjenningsinformasjonskapsel som brukes til å opprettholde godkjenningsstatusen din. Navnet på informasjonskapselen får et langt, tilfeldig laget forledd, etterfulgt av _identity. Informasjonskapselen lagrer bare opplysninger som er nødvendige for å opprettholde en sikker og godkjent økt, og varer bare så lenge brukeren er godkjent i Craft.
— *_username
Provider: this site
Expiration: Persistent
Description: Dersom du har merket av La meg være pålogget under påloggingen, brukes denne informasjonskapselen til å huske brukernavnet til neste godkjenning.
— CRAFT_CSRF_TOKEN
Provider: this site
Expiration: Session
Description: Beskytter oss og deg som bruker mot angrep fra ondsinnet datakode (CSRF).

Statistikk

Statistikkinformasjonskapsler hjelper oss å forstå hvordan besøkende samhandler med nettsteder, gjennom å samle inn og formidle informasjon i anonym form.

Markedsføring

Markedsføringsinformasjonskapsler brukes til å spore besøkende over flere nettsteder. Formålet er å vise annonser som er relevante og engasjerende for den enkelte brukeren, og som dermed får større verdi for utgiverne og tredjepartsannonsørene.
Skjul detaljer